About Us
MESSAGE
The human heart is an organ essential for sustaining life, continuously pumping blood throughout the body by repeating approximately 100,000 cycles of contraction and relaxation each day, amounting to nearly three billion beats over a lifetime. I have been deeply fascinated by this remarkable dynamism and have devoted my passion to cardiovascular research.
However, in exchange for its extraordinary functional demands, the human heart largely loses its capacity for cell division and proliferation, making self-regeneration extremely limited once injury occurs. Our research focuses on developing technologies to efficiently derive cardiomyocytes from human induced pluripotent stem cells (hiPSCs) and to construct functional cardiac tissues. By leveraging these technologies, we aim to establish regenerative therapies for intractable cardiovascular diseases.
Guided by the principles of passion, integrity, and creativity, our laboratory is committed not only to hiPSC-based cardiac regenerative therapies but also to exploring diverse approaches to develop novel treatments for cardiovascular diseases.
Let’s join us in pursuing research aimed at the fundamental cure of cardiovascular disease.
Prof.
Shugo Tohyama, MD, PhD

GALLERY
Research video
Human iPSC-cardiomyocytes before metabolic selection
Human iPSC-cardiomyocytes after metabolic selection
Time-lapse of cardiac spheroids formation
Time-lapse of metabolic selection
Cardiac fibers derived from human iPSCs
Engineered heart tissue derived from human iPSCs
Human iPSC-cardiomyocytes after metabolic selection
Cardiac spheroids derived from human iPSCs
Tubular engineered heart tissue derived from human iPSCs
Research picture





Other


Travel Abstract Awards
at ISSCR 2025 (Umei)









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